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RK-701 is a highly selective potent and low-toxicity inhibitor of histone methyltransferases G9a and GLP1 with IC50 values of 23-27 nM and 53 nM RK-701 treatment induces fetal globin expression in human erythroid cells and in mice and plays an essential role in -globin induction RK-701 is used in the research of sickle cell disease
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CY-09 is a selective, direct inhibitor of the NLRP3 inflammasome used for biochemical and cellular research. It binds the ATP-binding motif of the NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, preventing inflammasome assembly and activation. For research use only.
Selective NLRP3 inhibitor targeting the NACHT domain
Inhibits NLRP3 ATPase activity to block inflammasome activation
High purity compound suitable for biochemical and cellular assays
Available as a solid powder, stable under recommended storage conditions
Supplied in research-scale pack sizes for laboratory experiments
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
CY-09 is a selective, direct inhibitor of the NLRP3 inflammasome that binds the ATP-binding motif of the NLRP3 NACHT domain and inhibits NLRP3 ATPase activity, suppressing inflammasome assembly and activation. Supplied as a high-purity solid for research use.
Selective NLRP3 inhibitor targeting the ATP-binding motif
Inhibits NLRP3 ATPase activity to block inflammasome activation
High purity solid form for research applications
Light yellow to yellow appearance
Stable when stored at recommended low temperatures
Available in small research sizes, including 25 mg
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
IL-2R beta (CD122) a type cytokine receptor expressed on T lymphocytes is a receptor for IL-2 (Kd 1 nM approximately)[1] IL-2R beta mediates T cell immune responses such as stimulating T cell proliferation and activating lymphokine-activated killer cells[2] IL-2R beta/CD122 Protein Cynomolgus (HEK293 His) is a recombinant cynomolgus IL-2R beta (A27-D239) with a C-Terminal His tag which is produced in HEK 293
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RK-701 is a selective, non-genotoxic small-molecule inhibitor of the histone methyltransferase G9a (EHMT2) developed for research use. It exhibits potent biochemical and cellular activity and includes manufacturer-provided data for solubility, stability, and purity to support experimental planning.
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
TNF-alpha/TNFSF2 protein binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR It induces tumor cell death fever cachexia cell proliferation and cell differentiation It also causes insulin resistance and GKAP42 protein degradation in adipocytes Additionally it plays a role in angiogenesis osteoclastogenesis and IL12 production in dendritic cells TNF-alpha/TNFSF2 Protein Cynomolgus (N-His) is the recombinant cynomolgus-derived TNF-alpha/TNFSF2 protein expressed by E coli with N-6 His labeled tag
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